Inorganic and Organic Chemistry(CP4006) - Preparation and Recrystallisation of Aspirin

Synopsis The purpose of this experiment was for students to prepare some open organic fertiliser deepen and to purify the compound by recrystallisation. This experiment allowed the students to give the synthesis of acetylsalicylic acid, acquire the skills of recrystallisation using chemical design filtration and reinforce the proficiency of the run point determination. The method consumption to synthesize acetylsalicylic acid was esterification by reacting salicylic acid with acetic anhydride with the movement of dehydrating agent, conc. sulphuric acid, to festinate up the reaction. Having obtained the crude acetylsalicylic acid which was button up impure, recrystallisation was conducted to remove the impurities. The aspirin harvested at the end of the experiment was 1.19g with the dowery yield of 37.8%. The melting point observed from the product ranged from 133°C to 137°C. Introduction Acetylsalicylic acid or comm only(prenominal) known as aspirin is an org anic compound belong to ester group with condensed structural formula of CH3COOC6H4COOH. (2) (2) C6H4(OCOCH3)COOH 3D baby-sit of chemical structure of aspirin acetylsalicylic acid derived from salicylic acid is categorized as nonsteroidal anti-inflammatory drugs or NSAIDs.

It is commonly employ to centre pip-squeak pain and aches (analgesic), write down fever (antipyretic), thin the blood (anticoagulation), slim the inflammation much(prenominal) as rheumatism and arthritis (anti-inflammatory), enhances the elimination of uric acid (uricosuric) and snip the risk of stroke, heart attack and ! another(prenominal) heart problems in long-term low-doses. The related compound of aspirin from willow struggle (Salix alba) has been used to relieve pain and reduce fever since hundred of long time a go. The Chinese used the willow speak as a remedy in 500 BC piece of music the record that willow bark could ease aches and pains and trim fever was written by Hippocrates, a Greek physician in 400 BC. However, it was only until 1763 when the Reverend Edward Stone notice the effectiveness of willow bark in reduce fever In... If you want to get a estimable essay, order it on our website: OrderCustomPaper.com

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